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Hemlock

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Hemlock

Post by sujin007 on Fri Nov 16, 2012 1:40 pm

Hemlock is one of the most widely known poisons. The most important and toxic alkaloid in hemlock is coniine, which has a chemical structure similar to nicotine.

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Re: Hemlock

Post by sujin007 on Fri Nov 16, 2012 1:42 pm

Coniine is a neurotoxin, which disrupts the workings of the central nervous system and is toxic to humans and all classes of livestock.

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Re: Hemlock

Post by sujin007 on Fri Nov 16, 2012 1:43 pm

Coniine causes death by blocking the neuromuscular junction in a manner similar to curare; this results in an ascending muscular paralysis with eventual paralysis of the respiratory muscles which results in death due to lack of oxygen to the heart and brain.

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Re: Hemlock

Post by sujin007 on Fri Nov 16, 2012 1:45 pm

Death can easily be prevented by artificial ventilation until the effects have worn off 48–72 hours later. Ingestion of Poison Hemlock in any quantity can result in respiratory collapse and death.

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Re: Hemlock

Post by sujin007 on Fri Nov 16, 2012 1:46 pm

For an adult the ingestion of more than 100 mg of coniine, approximately 6 to 8 fresh leaves, or a smaller dose of the seeds or root, may result in fatality.

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Re: Hemlock

Post by sujin007 on Fri Nov 16, 2012 1:48 pm

Despite its deadly reputation, poison hemlock has been used as a sedative and for its antispasmodic properties. It was also used by Greek and Persian physicians for a variety of problems, such as arthritis.



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Re: Hemlock

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